浙江大学西湖学术论坛第192次会议—“细胞信号转导与疾病研讨会”定于2018年10月29日在杭州召开。论坛以“细胞信号传导与疾病的关系”为主题，邀请英国皇家科学院院士Nicholas Tonks等八位在信号传导研究领域顶尖的外籍教授，与西湖大学校长施一公院士等国内领域的专家一同围绕最新研究进展做公开学术报告，并就相关领域的前沿科学问题与发展趋势进行积极深入的探讨。最是一年秋色好，喜看丹桂万重香。值此金秋佳节之际，诚邀浙江大学师生共赴一场信号传导的学术盛宴：领略顶级学术大师风采，促进国内外科研学者携手合作。
会议具体事宜如下：
一、会议内容：
信号传导是细胞行驶功能的基本方式，信号传导异常与疾病的发生发展密切相关，信号传导关键分子也是目前疾病干预的主要靶点。该领域的研究正成为近年以及未来数年的研究热点，为了解疾病相关信号传导研究的前沿进展，本次会议将主要围绕以下内容做公开学术报告：
1.经典信号传导通路；
2.主要蛋白磷酸酶在器官发育与再生，炎症与肿瘤中作用。
二、会议时间
2018年10月29日 8：30-17:20
三、会议地点
浙江大学紫金港校区医学院科研辅楼报告厅
四、主办单位
浙江大学
中国科学院学术与出版工作委员会
《中国科学：生命科学》杂志社
华人生物学家协会
五、会议议程：
Main Hall at Affiliated Building, Zhejiang UniversitySchool of Medicine, Zijingang Campus（浙江大学医学院辅楼报告厅）
8:30-8:50 OpeningCeremony Moderator：Prof. Yuehai Ke
8:30-8:40 WelcomeSpeech Prof. Gen-sheng Feng & Prof.Yuehai Ke
8:40-8:50 GroupPhoto
Session One Moderator：Prof. Yuehai Ke
8:50-9:20 Prof. Yigong Shi
Institute of Biology,Westlake Institute for Advanced Study/Westlake University. P.R.China
“TBD”
9:20-9:50 Prof. Nicholas Tonks
Cold Spring Harbor Laboratory,New York, USA
“New approachesto exploiting PTP1B as a therapeutic target”
9:50-10:20 Prof. Kun-Liang Guan
Department of Pharmacologyand Moores Cancer Center, University of California atSan Diego. USA
“The Hippo pathway: regulation and function”
10:20-10:30 CoffeeBreak
Session Two Moderator：Prof. Gen-sheng Feng
10:30-11:00 Prof.Xinhua Feng
Life SciencesInstitute, Zhejiang University P.R.China
“Inactivation of TGF-beta Signaling by oncogenic ALK”
11:00-11:30 Prof.Nissim Hay
Department of Biochemistry andMolecular Genetics, College of Medicine, University of Illinois at Chicago USA
“Cell autonomous and systemic effects of Akt isoformson tumor development, progression, and metastasis”
11:30-12:00 Prof. Yi Sun
Dean, Institute of TranslationalMedicine, Zhejiang University. P.R.China
“SAG/RBX2 E3 ubiquitin ligase in lung cancer: fromtarget identification to drug discovery and clinical trial”
12:00-12:10 Prof. Gen-sheng Feng
Department of Pathology,Division of Biological Sciences, and Moores Cancer Center, University ofCalifornia at San Diego. USA
“Introduction of Science China Life Sciences”
12:10-13:00 Lunch(Light Meal at Conference Hall)
Session Three Moderator：Prof. Wei Yang
13:00-13:30 Prof. Mathias Heikenwalder
Division of ChronicInflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg GER
“On distinct types of chronic inflammation causingliver cancer”
13:30-14:00 Prof. Ying-zi Yang
Department of Developmental Biology, Harvard Schoolof Dental Medicine, Harvard Stem Cell Institute. USA
“Hepatic Hippo signaling represses liver tumor formation by regulatingWnt/β-catenin and Notch Signaling as well as the immune microenvironment”
14:00-14:30 Prof. Jin Zhang
University of California, SanDiego USA
“Illuminating the Biochemical Activity Architecture ofthe Cell”
14:30-15:00 Prof. Shixian Lin
Life SciencesInstitute, Zhejiang University P.R.China
“Chemicalbiology approaches for studying posttranslational modifications”
15:00-15:10 CoffeeBreak
Session Four Moderator：Prof. Yiting Zhou
15:10-15:40 Prof. Benjamin G. Neel
Laura and Isaac PerlmutterCancer Center, NYU Langone Health. USA
“Targeting SHP2 in Cancer”
15:40-16:10 Prof. Gen-sheng Feng
Department of Pathology,Division of Biological Sciences, and Moores Cancer Center, University ofCalifornia at San Diego. USA
“An efficient combination immunotherapy for livercancer by remodeling innate and adaptive immunity”
16:10-16:40 Prof. Yuehai Ke
School of Basic Medical Sciences,Zhejiang University. P.R.China
“Roles of macrophagephosphatase Shp2 in microenvironments”
16:40-17:10 Prof. Hongguang Xia
School of Basic Medical Sciences,Zhejiang University. P.R.China
“From bench to bed, new story of EGFR and Shp2”
17:10-17:20 ClosingCeremony Moderator: Prof. Gen-sheng Feng
浙江大学科学技术研究院
2018年10月24日